Table 2 Top 5 significant transcripts from M1, top 2 significant genes from M2, significant Gene Ontology terms from M3, and significant Reactome pathways from M4.
Tissue | Model | ID name | Effect | P |
|---|---|---|---|---|
Liver | Transcript (M1) | ENSRNOT00000074131 PNKD | 2.76 | 4.7 × 10–10 |
Transcript (M1) | ENSRNOT00000093245 TRIP12 | 2.15 | 1.2 × 10–6 | |
Transcript (M1) | ENSRNOT00000093735 TRIP12 | 1.67 | 0.00016 | |
Transcript (M1) | ENSRNOT00000022822 TRIP12 | 1.65 | 0.00021 | |
Transcript (M1) | ENSRNOT00000079452 TRIP12 | 1.63 | 0.00023 | |
Gene (M2) | ENSRNOG00000016963 TRIP12 | 1.66 | 3.5 × 10–5 | |
Gene (M2) | ENSRNOG00000014806 PNKD | 1.12 | 0.00520 | |
Gene ontology (M3) | GO:1901315 Negative regulation of histone H2A K63-linked ubiquitination | 0.52 | 0.00055 | |
Gene ontology (M3) | GO:2000780 Negative regulation of double-strand break repair | 0.48 | 0.00130 | |
Gene ontology (M3) | GO:2000779 Regulation of double-strand break repair | 0.37 | 0.01300 | |
Gene ontology (M3) | GO:0045995 Regulation of embryonic development | 0.30 | 0.04200 | |
Gene ontology (M3) | GO:0002181 Cytoplasmic translation | 0.29 | 0.05200 | |
Reactome pathway (M4) | R-RNO-6791226 Major pathway of rRNA processing in the nucleolus and cytosol | 0.29 | 0.05500 | |
Adrenal | Transcript (M1) | ENSRNOT00000075998 SUCO | 3.48 | 9.2 × 10–11 |
Transcript (M1) | ENSRNOT00000084058 SUCO | 2.18 | 4.9 × 10–5 | |
Transcript (M1) | ENSRNOT00000082271 PLEC | 2.10 | 8.9 × 10–10 | |
Transcript (M1) | ENSRNOT00000075936 SUCO | 1.95 | 0.00029 | |
Transcript (M1) | ENSRNOT00000088945 PLEC | 1.70 | 0.00160 | |
Gene (M2) | ENSRNOG00000026542 SUCO | 2.26 | 8.4 × 10–6 | |
Gene (M2) | ENSRNOG00000018413 PER3 | 1.63 | 0.00130 | |
Reactome pathway (M4) | R-RNO-212436 Generic Transcription Pathway | 0.49 | 0.00500 |