Figure 4

SPTY2D1-AS1 overexpression decreases tumor growth in vivo. Xenograft tumors were generated by subcutaneous injection with Cal62-Luc cells overexpressing SPTY2D1-AS1 (SPTY) or control (empty) vector. (A) Representative images of the bioluminescent signal of the generated tumors at the indicated time points. (B) Tumor radiance quantification at the indicated time points. (C) Generated tumors after excision. (D) Tumor weight of the generated tumors. Values represent mean ± SEM. *p < 0.05; **p < 0.01.