Figure 2

C57Bl/6 mice have greater motor impairment and stroke-induced weight loss compared to FVB/N mice. In contrast, FVB/N mice are more sensitive to the adhesive removal test. Effects of light exposures of 15 (C57Bl/6 n = 8, FVB/N n = 16), 18 (C57Bl/6 n = 10, FVB/N n = 14), and 20 min (C57Bl/6 n = 8, FVB/N n = 15) during stroke induction, prior to stroke, and 1, 3, and 7 days after stroke on: The hanging wire test in C57Bl/6 mice (a) or FVB/N mice (b), expressed as latency to fall (s); the adhesive removal test for C57Bl/6 (c) and FVB/N (d) mice, expressed as time to remove adhesives (s); change in body weight for the C57Bl/6 (e) and FVB/N (f) strains of mice, expressed as a change in percentage of the pre-stroke baseline weight. Data are presented as mean ± SEM, with *P < 0.05 vs pre-stroke, ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs sham, ^$P < 0.05 vs 15 min, two-way RM ANOVA followed by Tukey’s multiple comparisons test.