Figure 1
From: Increase of Parkin and ATG5 plasmatic levels following perinatal hypoxic-ischemic encephalopathy
Investigation of mitophagy in newborns at birth and correlation with clinical endpoints. (A) Parkin plasma levels measured by ELISA in healthy, babies not needing TH and severe HIE newborns. (B) Correlation between Parkin and pH at birth. (C) Parkin level stratification according to the base excess score in the whole cohort. (D) Correlation between Parkin and lactate release at birth. (E) Parkin level stratification according to resuscitation-at- birth score in the whole cohort (0–1 = CPAP assistance, 2–5 = from PPV to drugs). (F) Parkin level stratification according to Apgar score at 5 min in the whole cohort.
