Figure 2 | Scientific Reports

Figure 2

From: Pentosan polysulfate induces low-level persistent prion infection keeping measurable seeding activity without PrP-res detection in Fukuoka-1 infected cell cultures

Figure 2

Seeding activity in prion-infected cells treated with anti-prion compounds. Prion-infected N2a58 cells were treated with Congo Red, Alprenolol, or PPS from P0 to P6. For each passage, prion seeding activity (Log SD50/106 cells) was quantified from three independent experiments using RT-QuIC (mean ± standard deviation). Open circles and squares indicate N2a58/FK1 and N2a58/22L, respectively. Asterisks indicate less than the limit of detection (L.D.).

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