Figure 5

Smoking status and molecular alterations. (a) EGFR mutations in exon 6, 18, 19 and 21 found in the current smokers (red), former smokers (yellow) and never smokers (blue). (b) KRAS mutations in exon 12, 13 and 61 found in the current smokers (red), former smokers (yellow) and never smokers (blue). (c) BRAF, TP53, MET mutations, JAK2 mutations and loss and fusions in ALK, RET and ROS1 found in the current smokers (red), former smokers (yellow) and never smokers (blue). NOTE: For alterations with *, BH adjusted p value from Fisher’s exact test was < 0.05.