Table 1 Clinical characteristics of the patient population (eligible population).

Sex

289 M, 189 F, 2 missing

21 M, 15 F

14 M, 9 F

Age at Dx

Median 65 (18–86)

Median 49 (27–82)

Median 63 (23–79)

Age at registration

Median 65 (19–87)

Median 51 (31–83)

Median 63 (23–80)

Smoking history

Non-smoker

Ex-smoker

Current smoker

Unknown

83 (17.3%)

327 (68.1%)

65 (13.5%)

5 (1%)

16 (44.4%)

15 (41.7%)

2 (5.6%)

3 (8.3%)

11 (47.8%)

11 (47.8%)

0

1 (4.3%)

Environmental

Asbestos

Chemical agent

Radiation

19 (4%)

18 (3.8%)

1 (0.2%)

1 (2.8%)

0

0

12 (52.2%)

0

1 (4.3%)

Histology (WHO)—From PATH CRF

Adenocarcinoma: 300 (62.5%)

Squamous cell carcinoma: 104 (21.7%)

Other (incl. large cell carcinoma): 76 (15.8%)

Type AB: 3 (8.35%)

Type B1: 4 (11.1%)

Type B2: 7 (19.45%)

Type B3: 4 (11.1%)

Type C: 14 (38.9%), including 2 epidermoid non-keratinizing carcinoma, 2 basaloid carcinoma, 2 undifferentiated and 7 unknown

Unknown: 4 (11.1%)

Epithelioid: 18 (78.3%)

Sarcomatoid: 1 (4.3%)

Biphasic: 2 (8.7%)

Desmoplastic: 1 (4.3%)

Unknown: 1 (4.3%)

Stage at registration (or diagnosis if registration if registration unknown)

(AJCC7)

0—1 (0.2%)

IA—84 (17.5%)

IB—53 (11%)

IIA—71 (14.8%)

IIB—46 (9.6%)

IIIA—92 (19.2%)

IIIB—22 (4.6%)

IV—101 (21%)

Unknown—10 (2.1%)

(Masoka)

Stage I—6 (16.7%)

Stage IIb—1 (2.8%)

Stage III—8 (22.2%)

Stage IVa—9 (25%)

Stage IVb—9 (25%)

Unknown—3 (8.3%)

Grade 1—7 (30.4%)

Grade 2—1 (4.3%)

Grade 3—2 (8.7%)

Unknown—13 (56.5)

Stage I—2 (8.7%)

Stage IB—1 (4.4%)

Stage II—5 (21.7%)

Stage III—7 (30.4%)

Stage IV—7 (30.4%)

Missing—1 (4.4%)

Localization

Main Bronchus—15 (3.1%)

Upper lobe—245 (51%)

Middle lobe—16 (3.3%)

Lower lobe—159 (33.1%)

Other bronchus—14 (2.9%)

Other—24 (5%)

Unknown—7 (1.4%)

Side:

Right—253 (52.7%)

Left—215 (44.8%)

Both—1 (0.2%)

Unknown—11 (2.3%)

Thymus—18 (50%)

Mediastinum—17 (47.2%)

Other—1 (2.8%)

Side:

Anterior—21 (58.3%)

Middle—1 (2.8%)

Posterior—2 (5.6%)

Unknown—12 (33.3%)

Parietal—18 (78.3%)

Both—4 (17.4%)

Other—1 (4.3%)

Side:

Right—18 (78.3%)

Left—5 (21.7%)

Curative surgery

Yes: 368 (76.7%)

No: 110 (22.9%)

Unknown: 2 (0.4%)

Yes: 23 (63.9%)

No: 13 (36.1%)

Unknown: 0

Yes: 6 (26.1%)

No: 17 (73.9%)

Unknown: 0

Curative RT

Yes: 80 (16.7)

No: 398 (82.9%)

Unknown: 2 (0.4%)

Yes: 20 (55.6%)

No: 16 (44.4%)

Unknown: 0

Yes: 4 (17.4%)

No: 19 (82.6%)

Unknown: 0

Chemotherapy

Yes: 233 (48.5%)

No: 245 (51%)

Unknown: 2 (0.4%)

Yes: 23 (63.9%)

No: 13 (36.1%)

Unknown: 0

Yes: 13 (56.5%)

No: 10 (43.5%)

Unknown: 0