Table 3 Measurements of center macular retinal and choroidal thickness according to timing of ILM peeling.

From: Effect of vitrectomy with silicone oil tamponade and internal limiting membrane peeling on eyes with proliferative diabetic retinopathy

 

Group 1

Group 2

P value‡

Percent change‡

 

P value†

 

P value†

Total retina (µm)

Baseline

315.50 ± 69.45

 

311.04 ± 63.20

 

0.218

 

Before SOR

316.53 ± 75.69 (+ 1.97%)

0.932

331.08 ± 89.48 (+ 7.70%)

0.230

0.151

0.283

3 months after SOR

293.26 ± 59.27 (− 6.00%)

0.022*

288.32 ± 60.08 (− 3.56%)

0.083

0.518

0.951

6 months after SOR

283.69 ± 60.82 (− 11.90%)

0.001*

273.82 ± 57.73 (− 9.12%)

0.016*

0.421

0.550

12 months after SOR

280.08 ± 58.43 (− 11.88%)

0.001*

270.50 ± 56.28 (− 11.09%)

0.006*

0.241

0.866

Outer retina (µm)

Baseline

80.12 ± 5.99

 

82.91 ± 5.80

 

0.102

 

Before SOR

80.78 ± 7.76 (+ 1.01%)

0.594

80.68 ± 3.79 (− 2.77%)

0.207

0.902

0.090

3 months after SOR

83.56 ± 7.67 (− 2.56%)

0.135

82.48 ± 5.47 (− 0.54%)

0.507

0.426

0.690

6 months after SOR

82.11 ± 11.47 (+ 1.17%)

0.517

83.04 ± 4.52 (+ 0.14%)

0.968

0.653

0.703

12 months after SOR

83.16 ± 8.55 (+ 3.09%)

0.111

83.29 ± 5.55 (+ 0.40%)

0.829

0.160

0.322

Inner retina (µm)

Baseline

235.62 ± 67.56

 

223.25 ± 57.57

 

0.293

 

Before SOR

236.28 ± 73.51 (+ 3.22%)

0.743

250.72 ± 89.95 (+ 13.62%)

0.053

0.067

0.255

3 months after SOR

209.53 ± 56.55 (− 8.81%)

0.016*

204.96 ± 58.65 (− 7.17%)

0.670

0.149

0.801

6 months after SOR

201.69 ± 55.77 (− 16.08%)

0.009*

190.87 ± 56.86 (− 11.85%)

0.062

0.673

0.486

12 months after SOR

196.80 ± 56.89 (− 17.01%)

0.002*

187.58 ± 54.83 (− 14.26%)

0.022*

0.834

0.661

Gc-IPL (µm)

Baseline

54.12 ± 22.75

 

44.72 ± 16.01

 

0.101

 

Before SOR

52.90 ± 20.70 (+ 8.93%)

0.783

50.60 ± 19.56 (+ 17.29%)

0.430

0.213

0.577

3 months after SOR

45.50 ± 15.77 (− 5.56%)

0.031*

43.70 ± 19.05 (− 0.72%)

0.470

0.241

0.650

6 months after SOR

41.07 ± 18.05 (− 17.53%)

0.002*

42.26 ± 18.01 (− 4.33%)

0.203

0.200

0.208

12 months after SOR

41.66 ± 14.76 (− 16.64%)

0.004*

38.91 ± 15.67 (− 11.25%)

0.043*

0.767

0.583

RNFL (µm)

Baseline

22.31 ± 7.71

 

18.70 ± 9.18

 

0.117

 

Before SOR

23.68 ± 6.37 (+ 18.79%)

0.437

21.12 ± 8.45 (+ 26.79%)

0.231

0.248

0.611

3 months after SOR

19.06 ± 10.88 (− 1.16%)

0.309

16.88 ± 5.37 (− 0.49%)

0.216

0.418

0.967

6 months after SOR

17.15 ± 4.12 (− 16.06%)

0.001*

16.16 ± 4.49 (− 5.61%)

0.085

0.594

0.314

12 months after SOR

15.62 ± 3.86 (− 21.41%)

 < 0.001*

15.04 ± 3.83 (− 11.81%)

0.028*

0.244

0.251

Choroid (µm)

Baseline

253.83 ± 72.79

 

261.26 ± 62.88

 

0.432

 

Before SOR

230.71 ± 67.33 (− 6.79%)

0.153

256.95 ± 80.84 (− 1.73%)

0.687

0.692

0.525

3 months after SOR

246.13 ± 57.78 (− 4.96%)

0.517

265.60 ± 68.28 (+ 2.88%)

0.964

0.283

0.403

6 months after SOR

239.53 ± 57.86 (− 2.47%)

0.233

259.60 ± 71.13 (+ 0.72%)

0.689

0.419

0.733

1 year after SOR

235.52 ± 49.79 (− 2.89%)

0.148

251.62 ± 74.21 (+ 0.77%)

0.593

0.364

0.726

  1. The values are presented as the mean ± standard deviation (percent change). Group 1, ILM peeling during SO injection surgery. Group 2, ILM peeling during SO removal surgery. †At each time point vs. baseline, paired t-test. ‡Group1 vs Group2, independent t-test. *P < 0.05, statistically significant. Gc-IPL ganglion cell-inner plexiform layer, ILM internal limiting membrane, RNFL retinal nerve fiber layer, SOR silicone oil removal.
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