Table 5 Shannon diversity indices and inflammatory scores by Gardnerella metagenomic subspecies at baseline at 16–20 gestational weeks.
From: HIV-associated vaginal microbiome and inflammation predict spontaneous preterm birth in Zambia
Shannon Diversity Index | Inflammatory Score | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Median | IQR | coeff | 95% CI | p | Median | IQR | coeff | 95% CI | p | |
Gardnerella—“other” | 0.44 | 0.21–0.85 | ref | – | – | 0.14 | − 1.49 to 0.96 | ref | – | – |
HIV− (n = 77) | 0.44 | 0.20–0.81 | ref | – | – | 0.03 | − 1.33 to 0.93 | ref | − | – |
HIV+ (n = 26) | 0.39 | 0.22 to 0.88 | ref | – | – | 0.21 | − 2.31 to 1.02 | ref | – | – |
Gardnerella—1 | 0.82 | 0.70–1.35 | 0.43 | 0.26,0.60 | < .001 | 0.51 | − 0.33 to 1.06 | 0.53 | − 0.06,1.12 | 0.08 |
HIV− (n = 29) | 0.79 | 0.69–1.35 | 0.42 | 0.23,0.62 | < .001 | 0.51 | − 0.23 to 1.07 | 0.51 | − 0.17,1.18 | 0.1 |
HIV+ (n = 13) | 1.06 | 0.76–1.26 | 0.46 | 0.15,0.78 | 0.005 | 0.53 | − 0.57 to 1.04 | 0.70 | − 0.40,1.81 | 0.2 |
Gardnerella—2 | 1.54 | 1.10–1.94 | 0.95 | 0.78,1.12 | < .001 | 0.91 | 0.13–1.29 | 0.92 | 0.44,1.41 | < .001 |
HIV− (n = 30) | 1.53 | 1.03–1.96 | 0.97 | 0.76,1.19 | < .001 | 0.83 | 0.03–1.30 | 0.78 | 0.16,1.39 | 0.01 |
HIV+ (n = 46) | 1.54 | 1.19–1.91 | 0.91 | 0.65,1.16 | < .001 | 0.93 | 0.35–1.29 | 1.27 | 0.49,2.05 | 0.002 |
