Figure 5 | Scientific Reports

Figure 5

From: In vitro and in ovo impact of the ionic dissolution products of boron-doped bioactive silicate glasses on cell viability, osteogenesis and angiogenesis

Figure 5

(a) Representative macroscopic images of the CAM assay for the control group and the BG groups after an incubation time of 1 (D1), 4 (D4), and 7 (D7) days post transplantation. Cell transplant (transparent/white) exemplarily marked with [ +] in the first picture. The inner diameter of the silicone rings refers to 9 mm and was used as size reference. (b) Representative microscopic images of the in situ hybridization of CAM resectates after a seven-day incubation period for the control group and the BG groups. Human BMSCs were present in all groups, as indicated by dark staining of nuclei (in a range from violet to black) following hALU-labeling. To prove a correct function of the in situ hybridization, a positive control (pCT; BMSC pellet), was assessed as well. (c) Vessels per area 7 days (D7) post transplantation. Values are normalized to the control group indicated by the dashed line. [*] marks significant differences compared to the control group. Significant differences between the B-doped BGs are highlighted with brackets.

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