Table 2 Results of the QLF measurements in different groups: ΔF max (fluorescence loss [%]) shows the highest value of ΔF measured within the region of interest and is an indication for the maximum lesion depth (SD: standard deviation).

Time	Group	Minimum	Maximum	Mean	SD	Group comparison
ΔFmax T-demin	I: SDF	− 45.8	− 20.3	− 33.97	6.75	p = 0.276
	II: Bifluorid 12	− 41.4	− 13.2	− 30.69	7.94
	III: Cervitec F	− 50.3	− 26.4	− 35.51	6.07
	Negative control	− 40.1	− 30.5	− 33.56	3.89
ΔFmax T07	I: SDF	− 44.8	− 22.0	− 33.17	6.55	p = 0.152
	II: Bifluorid 12	− 49.6	− 27.5	− 37.66	6.87
	III: Cervitec F	− 43.5	− 20.7	− 34.32	5.86
ΔFmax T14	I: SDF	− 50.0	− 28.6	− 37.96^a,b	8.07	p = 0.021*
	II: Bifluorid 12	− 50.0	− 30.2	− 40.41^a	6.20
	III: Cervitec F	− 40.0	− 19.3	− 33.01^b	6.91
ΔFmax T21	I: SDF	− 59.5	− 21.2	− 39.23	11.60	p = 0.090
	II: Bifluorid 12	− 61.8	− 28.6	− 39.89	8.32
	III: Cervitec F	− 41.0	− 19.4	− 33.18	6.14
ΔFmax T28	I: SDF	− 52.4	− 26.8	− 38.14^a	8.71	p < 0.001*
	II: Bifluorid 12	− 50.9	− 26.2	− 34.53^a	6.37
	III: Cervitec F	− 46.8	− 9.80	− 24.24^b	9.98
	Negative control	− 45.2	− 30.6	− 34.98^a,b	6.00

*Different superscript letters indicate significant differences between the groups.

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