Figure 5 | Scientific Reports

Figure 5

From: Cancer genomic profiling identified dihydropyrimidine dehydrogenase deficiency in bladder cancer promotes sensitivity to gemcitabine

Figure 5

Nucleic acid-related metabolites after exposure to gemcitabine. Nucleic acid-related metabolites in HEK293 cells and DPD-overexpressing HEK293 cells cultured in medium containing 0 or 6.67 nM gemcitabine for 24 h. The concentrations of metabolites when exposed to gemcitabine were corrected against those not exposed to gemcitabine. Boxes, mean; bars, ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 (Student’s t-test).

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