Table 2 Univariate associations with poor functional outcomes (mRS 3–6) and mortality and hematoma expansion.

From: Irregular shape as an independent predictor of prognosis in patients with primary intracerebral hemorrhage

Variable

90-day poor outcome

90-day mortality

HE

OR

95% CI

P value

OR

95% CI

P value

OR

95% CI

P value

Age (years)s

1.037

1.020–1.054

< 0.001

1.032

1.009–1.055

0.006

0.984

0.957–1.012

0.261

Sex (male)

0.988

0.678–1.438

0.948

0.975

0.568–1.673

0.926

0.352

0.153–0.811

0.014

History of hypertension

1.608

0.843–3.067

0.150

1.675

0.582–4.823

0.339

1.322

0.390–4.489

0.654

History of diabetes

1.229

0.698–2.161

0.475

1.196

0.560–2.553

0.643

0.940

0.353–2.502

0.901

First systolic BP (mmHg)

1.016

1.009–1.022

< 0.001

1.025

1.015–1.034

< 0.001

1.009

0.998–1.021

0.100

Heart rate

1.012

1.002–1.023

0.021

1.024

1.011–1.038

< 0.001

0.991

0.971–1.011

0.373

Temperature

1.769

0.915–3.421

0.090

2.120

0.906–4.962

0.083

0.657

0.179–2.412

0.527

Initial hematoma volume (mL)

1.043

1.033–1.054

< 0.001

1.039

1.029–1.048

< 0.001

1.025

1.012–1.038

< 0.001

IVH

3.283

2.258–4.772

< 0.001

3.576

2.125–6.018

< 0.001

1.071

0.547–2.097

0.842

Location of ICH

1.355

0.757–2.425

0.307

0.577

0.283–1.178

0.131

0.800

0.297–2.154

0.659

Midline shift

1.258

1.189–1.332

< 0.001

1.260

1.186–1.339

< 0.001

1.140

1.046–1.243

0.003

Admission INR

1.365

0.567–3.290

0.488

1.646

0.640–4.234

0.301

1.109

0.271–4.531

0.886

Admission PT (s)

1.036

0.950–1.131

0.423

1.059

0.966–1.160

0.221

0.999

0.858–1.162

0.985

Admission APTT, s

0.912

0.863–0.965

0.001

0.972

0.901–1.048

0.461

1.016

0.927–1.114

0.731

Admission D-Dimer, > 0.55 mg/L FEU

2.809

1.928–4.092

< 0.001

3.518

2.096–5.905

< 0.001

1.032

0.533–1.998

0.926

Admission fibrinogen (g/L)

1.062

0.949–1.188

0.294

0.969

0.721–1.154

0.721

0.626

0.413–0.949

0.027

Irregular sign

4.380

3.003–6.389

< 0.001

5.233

2.991–9.155

< 0.001

3.776

1.950–7.312

< 0.001

GCS score on admission

0.900

0.842–0.962

0.002

0.862

0.790–0.940

0.001

0.958

0.851–1.078

0.474

Surgery

3.054

2.060–4.527

< 0.001

0.668

0396–1.129

0.132

7.674

3.941–14.942

< 0.001

  1. APTT = activated partial thromboplastin time, BP = blood pressure; CI = confidence interval; GCS = Glasgow Coma Scale; ICH = intracerebral hemorrhage; INR = international normalized ratio; IVH = intraventricular hemorrhage on presentation; mRS = modified Rankin Scale; NIHSS = NIH Stroke Scale; PT = prothrombin time. Values are n (%), mean ± SD, or median (interquartile range).
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