Table 2 Bivariate correlation analysis between PBCCs expression, vascular tissue expression and serum levels parameters.

From: Klotho expression in peripheral blood circulating cells is associated with vascular and systemic inflammation in atherosclerotic vascular disease

 

PBCCs expression (n = 92)

KL (a.u.)

DNMT1 (a.u.)

DNMT3A (a.u.)

r

P value

r

P value

r

P value

PBCCs expression

KL (a.u.)

1.000

     

DNMT1 (a.u.)

− 0.257*

 < 0.05

1.000

   

DNMT3A (a.u.)

− 0.166

0.12

0.692*

 < 0.0001

1.000

 

NFKB1 (a.u.)

− 0.281*

 < 0.01

0.580*

 < 0.0001

0.484*

 < 0.0001

TNF (a.u.)

− 0.310*

 < 0.01

0.487*

 < 0.0001

0.308*

 < 0.01

IL10 (a.u.)

0.500*

 < 0.0001

− 0.253*

 < 0.05

− 0.235*

 < 0.05

TNF/IL10

− 0.509*

 < 0.0001

0.397*

 < 0.001

0.306*

 < 0.01

Serum levels

sKL (pg/mL)

0.173

0.11

− 0.186

0.08

− 0.041

0.70

TNFα (pg/mL)

0.162

0.12

− 0.198

0.16

0.283*

 < 0.01

IL10 (pg/mL)

0.253*

 < 0.05

− 0.403*

 < 0.0001

− 0.155

0.14

TNFα/IL10

− 0.186

0.08

0.334

 < 0.01

0.069

0.52

 

Vascular tissue expression (n = 92)

TNF (a.u.)

IL10 (a.u.)

TNF/IL10

 

r

P value

r

P value

r

P value

PBCCs expression

KL (a.u.)

− 0.168

0.13

0.159

0.15

− 0.337*

 < 0.01

DNMT1 (a.u.)

0.353*

 < 0.01

0.069

0.53

0.236*

 < 0.05

DNMT3A (a.u.)

0.309*

 < 0.01

0.104

0.35

0.184

0.10

NFKB1 (a.u.)

0.379*

 < 0.001

− 0.006

0.95

0.302*

 < 0.01

TNF (a.u.)

0.275*

 < 0.05

0.037

0.74

0.196

0.08

IL10 (a.u.)

− 0.061

0.58

0.143

0.19

− 0.270*

 < 0.05

TNF/IL10

0.166

0.13

− 0.125

0.26

0.311*

 < 0.01

Serum levels

sKL (pg/mL)

− 0.179

0.11

− 0.078

0.49

− 0.070

0.54

TNFα (pg/mL)

− 0.185

0.10

− 0.021

0.85

− 0.144

0.20

IL10 (pg/mL)

− 0.244*

 < 0.05

0.137

0.22

− 0.302*

 < 0.01

TNFα/IL10

0.166

0.14

− 0.137

0.22

0.233*

 < 0.05

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