Figure 3
From: Murine cardiac fibrosis localization using adaptive Bayesian cardiac strain imaging in vivo
Monitoring cardiac remodeling using ES longitudinal strain images. (A) Top row: Temporal progression of ES longitudinal strain images from BL to Day 14 (D14) in a female BALB/CJ mouse after MI surgery. Strain display dynamic range is from − 20 to + 20%. Negative strain value (blue) = myocardial wall shortening, positive strain value (red) = myocardial wall elongation and zero strain value (light green) = no wall motion. Bottom row: Cardiac fibrosis maps estimated using the ES longitudinal strain images presented on the top row. Red = fibrotic region, green = non-fibrotic region. (B) Top row: Box and whisker plots demonstrating temporal variation and inter-group comparison [MI (n = 10), IR (n = 13) and Sham (n = 8)] of PFM estimated from longitudinal strain (PFMLongitudinal) in the anterior myocardial segments. Bottom row: Box and whisker plots demonstrating temporal variation and inter-group comparison (MI, IR and Sham) of PFMLongitudinal in the posterior myocardial segments. Friedman’s test with Bonferroni–Dunn post hoc test was used. Symbol definitions: BL—Baseline, D1—Day 1, D2—Day 2, D7—Day 7, D14—Day 14, Squares—mean, Diamonds—outliers, whiskers—1.5 × IQR (Inter-quartile range), box—25th to 75th percentiles, *p < 0.05, **p < 0.01, ***p < 0.001.
