Table 2 Substantially altered metabolites between MTC and healthy groups using t test analysis.

From: Gas chromatography-mass spectrometry-based untargeted metabolomics reveals metabolic perturbations in medullary thyroid carcinoma

Metabolites

RT (min)

VIP

P value

FDR

Linoleic acid

21.14

1.95

2.49E−08

1.90E−06

Leucine

19.15

2.00

1.24E−07

4.70E−06

Linolenic acid

22.66

1.94

2.03E−07

5.13E−06

Palmitic acid

19.61

1.67

1.86E−05

0.000354

Glutamine

17.008

1.66

3.53E−05

0.00046

Glycerol-mono-phosphate

16.59

1.63

3.63E−05

0.00046

Inositol-4-monophosphate

23.26

1.58

0.000159

0.001727

Uric acid

20.36

1.45

0.000712

0.006765

Arachidonic acid

22.49

1.45

0.001053

0.008895

Stearic acid

21.39

1.26

0.002002

0.015214

Aspartic acid

14.12

1.18

0.006998

0.044165

Alpha-ketoglutarate

14.75

1.23

0.007452

0.044165

2-Ketoisocaproic acid

9.97

1.24

0.007555

0.044165

  1. FDR false discovery rate, RT retention time, VIP variable importance in the projection.
  2. P values are from the student t test which considered < 0.05 statistically significant.
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