Figure 5
PCBP1 selectively binds to mRNA to regulate alternative splicing. (A) Venn diagram showed the overlap of PCBP1-bound peak’s genes and PCBP1-regulated alternatively splicing genes, and the PCBP1-bound peak’s genes is the union of two IP samples. LogP: log2 pvalue of enrichment terms. (B) Bar plot exhibited the most enriched GO biological process results of the overlap peak’s genes in figA, that making use of analyses by Metascape. (C) IGV-sashimi plot showed the UPF1-bound sites across mRNA of PML. The transcript of the gene was plotted at the bottom of the graph. (D) IGV-sashimi plot showed the UPF1-regulated alternative splicing events across mRNA of Pml. The transcript of the gene was plotted at the bottom of the graph and on the right was a model diagram of splicing events.
