Figure 2

Representative examples of fluorescence intensity changes. A representative example of each IDC, DCIS, low-grade DCIS, and normal breast tissue (N = 1) is indicated. (a) Fluorescence intensity changes in the areas shown by the squares in the visible light images in panels (b–e). (b–e) Visible light images, 5 min FI images with pseudocolor, and HE-stained images of various samples. The green lines indicate areas of malignant cells. (b) Invasive ductal carcinoma. (c) Middle/high-grade DCIS. (d) Low-grade DCIS. (e) Normal breast tissue, including normal mammary glands. The scale bars indicate 5 mm.