Table 1 Actual and coded levels of the variables studied in BBD.

From: Application of Box-Behnken design for optimization of phenolics extraction from Leontodon hispidulus in relation to its antioxidant, anti-inflammatory and cytotoxic activities

 

Levels used

 

Low (− 1)

Middle (0)

High (1)

Independent variables

X1: ethanol/water ratio%

50

72.5

95

X2: extraction time

24 h

48 h

72 h

X3: material/solvent ratio

1:20

1:15

1:10

Dependent variables

Y1: Yield (gm)

   

Y2: Total phenolic

content (μg/mg)

   
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