Table 6 Sequential model fitting for the total phenolic content.

From: Application of Box-Behnken design for optimization of phenolics extraction from Leontodon hispidulus in relation to its antioxidant, anti-inflammatory and cytotoxic activities

Source

Sum of squares

Mean square

DF

F-value

P-value

Remarks

Sequential sum of squares

Mean

1.140E + 005

1.140E + 005

1

   

Linear

565.89

188.63

3

1.14

0.3684

 

2F

234.96

78.32

3

0.41

0.7494

 

Quadratic

1693.57

564.52

3

18.24

0.0011*

Suggested

Cubic

19.84

6.61

3

0.13

0.9345

Aliased

Residual

196.83

49.21

4

   

Total

1.167E + 005

6862.46

17

   

Lack of fit tests

Linear

1948.37

216.49

9

4.40

0.0837

 

2F

1713.41

285.57

6

5.80

0.0553

 

Quadratic

19.84

6.61

3

0.13

0.9345

Suggested

Cubic

0.000

 

0

  

Aliased

Pure error

196.83

49.21

4

   
 

Std. Dev

R-Squared

Adjusted

R-Squared

Predicted

R-Squared

PRESS

 

Model summary statistics source

Linear

12.85

0.2087

0.0261

− 0.5618

4234.10

 

2F

13.82

0.2954

− 0.1274

− 2.2271

8748.79

 

Quadratic

5.56

0.9201

0.8173

0.7695

624.92

Suggested

Cubic

7.01

0.9274

0.7096

 

+ 

Aliased

  1. *statistically significant: p ˂ 0.05.