Figure 6

Bronchi (Br) and surrounding stroma of AregKO mice (HDM-sensitized). (a) Optical microscope image (HE stained) and (b) SEM image (Grocott stained) of pulmonary tissue. (c) Optical microscope image (HE stained) and (d) SEM image (Grocott stained) of Br. (e) Optical microscope image (HE stained) and (f) SEM image (Grocott stained) of enlarged Br and interstitium. (a–d) Edematous changes around the bronchi are seen. (e, f) Amorphous substrate of the interstitium (arrow) is stained without fibrous tissue. All scale bars show 100 μm length.