Table 3 Table showing percentage values of AT8-immunopositive neurons with AIS length and/or position changes in compared to AT8-immunonegative neurons in AD and control cases.

From: Pyramidal cell axon initial segment in Alzheimer´s disease

 

AD cases

Control cases

AT8 + neurons with AIS changes

(29 out of 53) 54.7%

(41 out of 73)

56.2%

AT8 + neurons with no AIS changes

(24 out of 53) 45.3%

(32 out of 73)

43.8%

AT8 + neurons with AIS changes in AIS length and position

(6 out of 53) 11.3%

(18 out of 73)

24.7%

AT8 + neurons with changes only in AIS position

(7 out of 53) 13.2%

(8 out of 73)

11%

AT8 + neurons with AIS proximal shift

(10 out of 13) 76.9%

(23 out of 26)

88.5%

AT8 + neurons with AIS distal shift

(3 out of 13) 23.1%

(3 out of 26)

11.5%

AT8 + neurons with changes only in AIS length

(16 out of 53) 30.2%

(15 out of 73)

20.5%

AT8 + neurons with AIS lengthening

(18 out of 22) 81.8%

(17 out of 33)

51.5%

AT8 + neurons with AIS shortening

(4 out of 22) 18.2%

(16 out of 33)

48.5%

  1. Note that some AT8-immunopositive neurons may contain more than one type of AIS change at the same time.