Figure 1 | Scientific Reports

Figure 1

From: Growth differentiation factor 15 as a novel diagnostic and therapeutic marker for autoimmune hepatitis

Figure 1The alternative text for this image may have been generated using AI.

(A) Comparison of serum GDF15 levels in patients with liver diseases. Serum GDF15 levels were significantly higher in patients with AIH than in those with HB or PBC and healthy controls (p < 0.0001). In addition, serum GDF15 levels were significantly higher in HC patients than in PBC patients and healthy controls (p < 0.005). (Wilcoxon test; p < 0.0001) (B) Comparison of serum GDF15 levels in patients with non-LC and LC. Serum GDF15 levels were significantly higher in patients with LC than in those with non-LC (Wilcoxon test; p < 0.0001). (C) Comparison of serum GDF15 levels among various liver diseases in patients with non-LC. Serum GDF15 levels were significantly higher in patients with AIH than in those with other liver diseases and healthy controls (p < 0.0001 or p < 0.005). (Wilcoxon test; p < 0.0001). GDF15, growth differentiation factor 15; AIH, autoimmune hepatitis; HB, hepatitis B; HC, hepatitis C; PBC, primary biliary cholangitis; LC, liver cirrhosis.

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