Figure 2
From: Acinetobacter baumannii response to cefiderocol challenge in human urine
Genetic analysis of β-lactamase and PBP genes of AB5075 (A) and AMA40 (B) A. baumannii strains. qRT-PCR of genes associated with β-lactams resistance, efflux pump, and porins expressed in cation adjusted Mueller Hinton, cation adjusted Mueller Hinton supplemented with 50% HU. Fold changes were calculated using double ΔCt analysis. At least three independent samples were used. LB was used as the reference condition. Statistical significance (p < 0.05) was determined by ANOVA followed by Tukey’s multiple-comparison test, one asterisks: p < 0.05; two asterisks: p < 0.01, and three asterisks: p < 0.001.
