Table 1 Demographics and clinical characteristics of patients.
Characteristic | Intermittent (n = 27) | Extended (n = 26) | P value |
|---|---|---|---|
Age (years)a | |||
(Mean ± SD) | 53.0 ± 17.61 | 57.8 ± 15.35 | 0.291 |
Sex, n (%)b | |||
Male | 14 (52%) | 12 (46%) | 0.678 |
Female | 13 (48%) | 14 (54%) | |
Mechanical Ventilation, n (%)b | 19 (70%) | 18 (69%) | 0.928 |
APACHE II score (Median & IQR)c | 11 (7.0–16.0) | 8.5 (6.75–13.25) | 0.275 |
Diabetes, n (%)b | 11 (41%) | 10 (38%) | 0.865 |
Smoking, n (%)d | 4 (15%) | 1 (4%) | 0.172 |
SCRa (Mean ± SD) | 1.8 ± 0.93 | 1.1 ± 0.54 | 0.002 |
ALTa (Mean ± SD) | 90.0 ± 191.04 | 74.7 ± 117.13 | 0.727 |
ASTa (Mean ± SD) | 127.0 ± 256.34 | 58.4 ± 61.10 | 0.183 |
WBCs (*109 /L)a(Mean ± SD) | 11.9 ± 5.81 | 11.3 ± 8.6 | 0.784 |
Temperature (oC ) a (Mean ± SD) | 37.4 ± 0.78 | 37.2 ± 0.46 | 0.475 |
Positive cultures, n (%)b | 12 (44.4%) | 15 (57.7%) | 0.414 |
Infection source, n (%)b,d | |||
Respiratory tract | 18 (66.7) | 15 (57.6) | 0.577 |
Wound | 1 (3.7) | 0 (0) | 1.000 |
Urinary tract | 2 (7.4) | 4 (15.3) | 0.420 |
Skin or soft tissue | 0 (0) | 2 (7.6) | 0.236 |
Abdominal | 0 (0) | 1 (3.8) | 0.491 |
Blood | 4 (14.8) | 4 (15.3) | 1.000 |
Respiratory and blood | 2 (7.4) | 0 (0) | 0.491 |
Vasopressors | 16 (59.3) | 10 (38.5) | 0.130 |
Concomitant antibiotics, n (%)b,d | |||
Vancomycin | 14 (51.9) | 4 (15.4) | 0.005 |
Aminoglycosides | 1 (3.7) | 2 (7.7) | 0.530 |
Clindamycin | 1 (3.7) | 2 (7.7) | 0.530 |
Quinolones | 12 (44.4) | 15 (57.7) | 0.335 |
Linezolid | 0 (0) | 2 (7.7) | 0.142 |