Table 5 Outcomes before propensity score adjustment.

From: The CeCORD-J study on collagenase injection versus aponeurectomy for Dupuytren's contracture compared by hand function and cost effectiveness

Group

Collagenase

Surgery

P value

Hand10 score

Baseline (mean ± SD)

15.5 ± 18.2

14.2 ± 15.4

0.76

1w (mean ± SD)

25.2 ± 23.7

46.1 ± 23.8

 < 0.01

2w (mean ± SD)

18.2 ± 20.6

36.2 ± 25

 < 0.01

4w (mean ± SD)

10.2 ± 13.9

16.8 ± 16.8

0.07

8w (mean ± SD)

8.1 ± 12.8

12.7 ± 14.5

0.15

26w (mean ± SD)

6.5 ± 10.3

7.9 ± 11.3

0.59

EQ-5D-5L score

Baseline (mean ± SD)

0.859 ± 0.145

0.81 ± 0.121

0.14

1w (mean ± SD)

0.775 ± 0.111

0.739 ± 0.085

0.17

2w (mean ± SD)

0.816 ± 0.116

0.754 ± 0.09

 < 0.05

4w (mean ± SD)

0.857 ± 0.125

0.784 ± 0.094

 < 0.05

8w (mean ± SD)

0.899 ± 0.109

0.817 ± 0.117

 < 0.01

26w (mean ± SD)

0.905 ± 0.134

0.841 ± 0.119

 < 0.05

Direct cost, yen (mean ± SD)

372,370 ± 262,517

582,147 ± 267,204

 < 0.01

PIP degree of extension deficit

Baseline (mean ± SD)

37.2 ± 23.6

46.9 ± 27.8

0.11

4w (mean ± SD)

17.2 ± 19.4

12.8 ± 14.9

0.32

26w (mean ± SD)

20.6 ± 21.1

14.6 ± 15.6

0.21

MP degree of extension deficit

Baseline (mean ± SD)

39.9 ± 20.5

36.5 ± 21.9

0.5

4w (mean ± SD)

7.3 ± 12.8

3.7 ± 6.4

0.18

26w (mean ± SD)

4.9 ± 9

4.5 ± 9.8

0.86

PIP degree of flexion

Baseline (mean ± SD)

93.8 ± 5.3

93.7 ± 7.7

0.92

4w (mean ± SD)

91.6 ± 7.9

86.6 ± 10.4

 < 0.05

26w (mean ± SD)

94.2 ± 7.1

93.5 ± 6.1

0.68

MP degree of flexion

Baseline (mean ± SD)

85.9 ± 6.8

84.6 ± 6.3

0.43

4w (mean ± SD)

84.1 ± 10.9

79.1 ± 8.6

 < 0.05

26w (mean ± SD)

87.5 ± 8.1

82.6 ± 6

 < 0.01

  1. w week, MP metacarpophalangeal, PIP proximal interphalangeal, SD standard deviation.