Table 2 Spearman correlation analyses between 90-day change in metabolite factor level and 90-day change in NT-proBNP.

From: Plasma metabolites associated with functional and clinical outcomes in heart failure with reduced ejection fraction with and without type 2 diabetes

Factor

Correlation

Overall

T2DM

Non-T2DM

T2DM vs Non-T2DM

P-value

Adj. P-value

Partial correlationa

Partial correlation P-value

Correlation

P-value

Partial correlationa

Partial correlation P-value

Correlation

P-value

Partial correlationa

Partial correlation P-value

P-value

1

0.220

0.002

0.008

0.220

0.002

0.076

0.419

0.075

0.423

0.390

3 × 10–4

0.394

3 × 10–4

0.022

2

− 0.291

3 × 10–5

4 × 10–4

− 0.294

3 × 10–5

− 0.248

0.007

− 0.250

0.007

− 0.392

2 × 10–4

− 0.395

2 × 10–4

0.269

3

0.017

0.814

0.831

0.016

0.819

         

4

0.191

0.007

0.019

0.191

0.007

0.128

0.175

0.128

0.177

0.264

0.016

0.271

0.014

0.332

5

0.198

0.005

0.017

0.196

0.006

0.215

0.020

0.218

0.019

0.167

0.131

0.172

0.123

0.733

6

0.106

0.133

0.217

0.106

0.136

         

7

0.102

0.151

0.218

0.101

0.156

         

8

− 0.239

0.001

0.004

− 0.240

0.001

− 0.146

0.117

− 0.146

0.117

− 0.328

0.002

− 0.327

0.003

0.183

9

0.127

0.074

0.138

0.129

0.070

         

10

− 0.097

0.173

0.225

− 0.096

0.177

         

11

− 0.057

0.427

0.504

− 0.054

0.447

         

12

0.015

0.831

0.831

0.014

0.847

         

13

0.147

0.039

0.084

0.148

0.038

0.217

0.019

0.218

0.019

0.058

0.604

0.052

0.646

0.266

  1. Significant values are in bold.
  2. aPartial correlations adjusted for treatment assignment.