Table 3 Spearman correlation analyses between 90-day change in metabolite factor level and 90-day change in 6-minute walk distance.

Factor	Correlation	Overall				T2DM				Non-T2DM				T2DM vs Non-T2DM
Factor	Correlation	P-value	Adj. P value	Partial correlation^a	Partial correlation P-value	Correlation	P-value	Partial correlation^a	Partial correlation P-value	Correlation	P-value	Partial correlation^a	Partial correlation P-value	P-value
1	− 0.012	0.886	0.912	− 0.011	0.890
2	0.265	0.001	0.011	0.264	0.001	0.308	0.003	0.308	0.003	0.203	0.108	0.202	0.113	0.499
3	0.009	0.912	0.912	0.009	0.916
4	0.073	0.369	0.768	0.074	0.368
5	− 0.152	0.058	0.188	− 0.153	0.057
6	− 0.070	0.385	0.768	− 0.071	0.383
7	− 0.178	0.026	0.141	− 0.179	0.026	− 0.080	0.450	− 0.079	0.454	− 0.292	0.019	− 0.283	0.025	0.184
8	− 0.022	0.789	0.912	− 0.022	0.787
9	0.058	0.473	0.768	0.06	0.459
10	− 0.023	0.779	0.912	− 0.023	0.775
11	0.171	0.033	0.141	0.173	0.031	0.253	0.015	0.256	0.015	0.107	0.400	0.104	0.419	0.363
12	0.060	0.457	0.768	0.06	0.459
13	− 0.014	0.864	0.912	− 0.013	0.875

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