Table 1 Summary of predicted effective concentrations of mixture for Case Study 1.

From: MRA Toolbox v. 1.0: a web-based toolbox for predicting mixture toxicity of chemical substances in chemical products

Toxic effect (%)

Predicted effective concentrations of mixture (μM) [CI]

CA

IA

QSAR-TSP

10

0.083 [0.057; 0.144]

0.077 [0.038; 0.160]

0.106 [0.078; 0.175]

20

0.166 [0.132; 0.193]

0.180 [0.135; 0.225]

0.180 [0.141; 0.212]

30

0.246 [0.208; 0.258]

0.293 [0.242; 0.314]

0.251 [0.208; 0.265]

40

0.327 [0.287; 0.339]

0.416 [0.359; 0.431]

0.324 [0.279; 0.336]

50

0.409 [0.373; 0.430]

0.552 [0.496; 0.578]

0.403 [0.360; 0.425]

60

0.497 [0.472; 0.529]

0.707 [0.662; 0.751]

0.491 [0.458; 0.527]

70

0.594 [0.583; 0.636]

0.890 [0.867; 0.955]

0.596 [0.579; 0.646]

80

0.711 [0.698; 0.758]

1.125 [1.112; 1.201]

0.732 [0.720; 0.788]

90

0.876 [0.809; 0.904]

1.478 [1.373; 1.528]

0.943 [0.864; 0.981]