Figure 5 | Scientific Reports

Figure 5

From: mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington’s disease phenotype

Figure 5The alternative text for this image may have been generated using AI.

Lack of mGluR5 decreases PSD95 expression in aged mice. Graphs show PSD95 (A, B and C) mRNA levels in the hippocampus of wild-type (WT), BACHD, mGluR5−/− and BACHD/mGluR5−/− mice at 2 (n = 4) (A), 6 (n = 4) (B) and 12 (n = 6) (C) months of age. mRNA levels were assessed by RT-qPCR, which was performed in triplicate and normalized to actin mRNA levels. Data represent the means ± SEM. *p < 0.05 and ***p < 0.01 by one-way ANOVA and Bonferroni's multiple comparisons test.

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