Table 2 KEGG Pathways of significantly different metabolites between sea level group and high-altitude Siachen group.
Id | Pathway name | Compound name | KEGG ID | HMDB |
|---|---|---|---|---|
1 | Phenylalanine, tyrosine and tryptophan biosynthesis | l-Phenylalanine | C00079 | HMDB0000159 |
l-Tyrosine | C00082 | HMDB0000158 | ||
2 | Glycine, serine and threonine metabolism | Choline | C00114 | HMDB0000097 |
N,N-Dimethylglycine | C01026 | HMDB0000092 | ||
Sarcosine | C00213 | HMDB0000271 | ||
Glycine | C00037 | HMDB0000123 | ||
Cysteine | C00097 | HMDB0000574 | ||
Pyruvate | C00022 | HMDB0000243 | ||
3 | Citrate cycle (TCA cycle) | Succinate | C00042 | HMDB0000254 |
Citrate | C00158 | HMDB0000094 | ||
cis-Aconitate | C00417 | HMDB0000072 | ||
Pyruvate | C00022 | HMDB0000243 | ||
Fumarate | C00122 | HMDB0000134 | ||
4 | Tyrosine metabolism | 3,4-Dihydroxymandelate | C05580 | HMDB0001866 |
l-Tyrosine | C00082 | HMDB0000158 | ||
Fumarate | C00122 | HMDB0000134 | ||
Pyruvate | C00022 | HMDB0000243 | ||
Acetoacetate | C00164 | HMDB0000060 | ||
5 | Glyoxylate and dicarboxylate metabolism | cis-Aconitate | C00417 | HMDB0000072 |
Citrate | C00158 | HMDB0000094 | ||
Glycine | C00037 | HMDB0000123 | ||
Acetate | C00033 | HMDB0000042 | ||
Pyruvate | C00022 | HMDB0000243 | ||
Formate | C00058 | HMDB0000142 | ||
6 | Glutathione metabolism | Glycine | C00037 | HMDB0000123 |
l-Cysteine | C00097 | HMDB0000574 | ||
7 | Nicotinate and nicotinamide metabolism | Nicotinamide d-ribonucleotide | C00455 | HMDB0000229 |
8 | Phenylalanine metabolism | l-Phenylalanine | C00079 | HMDB0000159 |
Hippurate | C01586 | HMDB0000714 | ||
l-Tyrosine | C00082 | HMDB0000158 | ||
9 | Cysteine and methionine metabolism | Cysteine | C00097 | HMDB0000574 |
Pyruvate | C00022 | HMDB0000243 | ||
10 | Taurine and hypotaurine metabolism | l-Cysteine | C00097 | HMDB0000574 |
Taurine | C00245 | HMDB0000251 | ||
11 | Butanoate metabolism | Acetoacetate | C00164 | HMDB0000060 |
Succinate | C00042 | HMDB0000254 | ||
12 | Pyruvate metabolism | Pyruvate | C00022 | HMDB0000243 |
(S)-Lactate | C00186 | HMDB0000190 | ||
Acetate | C00033 | HMDB0000042 | ||
Fumarate | C00122 | HMDB0000134 | ||
13 | Synthesis and degradation of ketone bodies | Acetoacetate | C00164 | HMDB0000060 |
14 | Glycolysis/gluconeogenesis | Pyruvate | C00022 | HMDB0000243 |
(S)-Lactate | C00186 | HMDB0000190 | ||
beta-d-Glucose | C00221 | HMDB0000122 | ||
Acetate | C00033 | HMDB0000042 | ||
15 | Histidine metabolism | Urocanate | C00785 | HMDB0000301 |
N(pi)-Methyl-l-histidine | - | - | ||
16 | Arginine biosynthesis | l-Citrulline | C00327 | HMDB0000904 |
Fumarate | C00122 | HMDB0000134 |
