Figure 2
Nmb deficiency in the nervous system does not affect food consumption, body weight and adiposity under standard diet. (A) Body weight of 6 month old control and NestinCre-Nmbflox/flox mice on standard diet. Each dot represents individual mice. (B) Food consumption of 6 month old control and NestinCre-Nmbflox/flox mice on standard diet. Each dot represents individual mice. (C) Organ weight isolated from 6 month old control and NestinCre-Nmbflox/flox mice on standard diet. n = 4 mice per group. (D) Intraperitoneal glucose tolerance test (IP GTT) of 6 month old control and NestinCre-Nmbflox/flox mice on standard diet. n = 6 mice per group. (E) Intraperitoneal insulin tolerance test (IP ITT) of 6 month old control and NestinCre-Nmbflox/flox mice on standard diet. n = 6–7 mice per group. (F) Oral glucose tolerance test (OGTT) of 6 month old control and NestinCre-Nmbflox/flox mice on standard diet. n = 8 mice per group. (G) Area under the curve of oral GTT under standard diet conditions. n = 8 mice per group. Data are shown as means ± SEM. Each dot represents individual mice. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001, ns not significant. For curve comparison, one-way ANOVA with Bonferroni correction was used, otherwise unpaired Student t-test was used to determine statistical significance.
