Figure 2

Risk of developing diabetic complications by group. Kaplan–Meier curve and hazard ratios of (a) retinopathy and (b) chronic kidney disease. The results were adjusted for age, sex, diabetes duration, systolic blood pressure, diastolic blood pressure, time of enrollment, BMI, HbA1c levels, LDL cholesterol levels, eGFR (not included in the analysis depicted by [b]), statin use, smoking status, alcohol consumption, and physical activity. Group 1. Reference (mild insulin resistance and beta-cell dysfunction) group. Group 2. “Severe beta-cell dysfunction” group. Group 3. “Severe insulin resistance” group. Group 4. “Severe insulin resistance and beta-cell dysfunction” group. aHR adjusted hazard ratio, CKD chronic kidney disease.