Table 3 Correlation analysis between candidate hub genes and immune cells in the TIMER2.0 database.
Hub genes | Purity | B cell | CD8+ T cell | CD4+ T cell | Macrophage | Neutrophil | DC | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
COR | P | COR | P | COR | P | COR | P | COR | P | COR | P | COR | P | |
JUN | 0.010 | 0.849 | − 0.038 | 0.48 | 0.235 | < 0.001 | − 0.002 | 0.975 | 0.281 | < 0.001 | 0.276 | < 0.001 | 0.179 | < 0.001 |
IL10 | − 0.472 | < 0.001 | 0.299 | < 0.001 | 0.396 | < 0.001 | 0.085 | 0.117 | 0.395 | < 0.001 | 0.293 | < 0.001 | 0.581 | < 0.001 |
CD34 | − 0.256 | < 0.001 | 0.164 | 0.002 | 0.275 | < 0.001 | 0.190 | < 0.001 | 0.207 | < 0.001 | 0.140 | 0.009 | 0.283 | < 0.001 |
MTOR | 0.045 | 0.405 | − 0.032 | 0.560 | 0.142 | 0.008 | 0.000 | 0.996 | 0.210 | < 0.001 | 0.225 | < 0.001 | 0.151 | 0.005 |
PTGS2 | − 0.501 | < 0.001 | 0.166 | 0.002 | 0.227 | < 0.001 | 0.255 | < 0.001 | 0.452 | < 0.001 | 0.314 | < 0.001 | 0.419 | < 0.001 |
PTPRC | − 0.444 | < 0.001 | 0.375 | < 0.001 | 0.555 | < 0.001 | 0.205 | < 0.001 | 0.473 | < 0.001 | 0.399 | < 0.001 | 0.595 | < 0.001 |
SELE | − 0.310 | < 0.001 | − 0.179 | < 0.001 | 0.224 | < 0.001 | − 0.115 | 0.033 | 0.104 | 0.055 | 0.141 | 0.009 | − 0.081 | 0.133 |
CSF1 | − 0.333 | < 0.001 | 0.171 | 0.001 | 0.284 | < 0.001 | 0.160 | 0.003 | 0.472 | < 0.001 | 0.452 | < 0.001 | 0.509 | < 0.001 |
APOB | 0.095 | 0.079 | − 0.176 | 0.001 | 0.118 | < 0.001 | − 0.132 | 0.028 | − 0.007 | 0.904 | 0.029 | 0.588 | − 0.138 | 0.010 |
MUC1 | − 0.216 | < 0.001 | 0.288 | < 0.001 | 0.062 | 0.252 | 0.278 | < 0.001 | 0.260 | < 0.001 | 0.297 | < 0.001 | 0.384 | < 0.001 |