Figure 4 | Scientific Reports

Figure 4

From: Identification of bronchoalveolar and blood immune-inflammatory biomarker signature associated with poor 28-day outcome in critically ill COVID-19 patients

Figure 4

Supervised orthogonal partial least squares discriminant analysis (OPLS-DA) obtained from critically ill COVID-19 patients, according to 28-day WHO-CPS. Patients were grouped according to the World Health Organization 10-point Clinical Progression Scale (WHO-CPS) at 28-day. A score value higher than 5 (D28-WHO-CPS > 5) defined a poor 28-day outcome, whereas a score value equal or lower than 5 (D28-WHO-CPS ≤ 5) defined a good 28-day outcome. (A) Loading plots summarize the relationship of the 20 most discriminating variables labeled according to their association to D28-WHO-CPS ≤ 5 (green dots) and D28-WHO-CPS > 5 (red dots). (B) VIP (Variable Influence on Projection) plots summarize the importance of the 20 most discriminating variables. Histogram is colored according to the variable associations to D28-WHO-CPS ≤ 5 (green bars) and D28-WHO-CPS > 5 (red bars). BALF bronchoalveolar lavage fluid.

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