Table 1 Literature data for solubility of anti-cancer drugs in supercritical carbon dioxide.
CO2 (1) + drug (2) | Temperature (K) | Pressure (MPa) | CO2 density (kg/m3) | Drug solubility* × 106 | No. data |
|---|---|---|---|---|---|
Sorafenib tosylate19 | 308–338 | 12–27 | 388–914 | 0.68–12.57 | 24 |
Sunitinib malate20 | 308–338 | 12–27 | 388–914 | 5–85.6 | 24 |
Azathioprine21 | 308–338 | 12–27 | 388–914 | 2.7–18.3 | 24 |
Busulfan22 | 308–338 | 12–40 | 383–971 | 32.7–865 | 32 |
Tamoxifen23 | 308–338 | 12–40 | 383–971 | 18.8–989 | 32 |
Letrozole24 | 318–348 | 12–36 | 319–922 | 1.6–85.1 | 20 |
Tamsulosin25 | 308–338 | 12–27 | 384–914 | 0.18–10.13 | 24 |
Capecitabine26 | 308–348 | 15.2–35.4 | 477–955 | 2.7–158.8 | 40 |
Paclitaxel27 | 308–328 | 10–27.5 | 654–915 | 1.2–6.2 | 21 |
5-Fluorouracil27 | 308–328 | 12.5–25 | 541–901 | 3.8–14.6 | 18 |
Thymidine27 | 308–328 | 10–30 | 325–928 | 1.2–8 | 25 |
Decitabine28 | 308–338 | 12–40 | 383–971 | 28.4–1070 | 32 |
