Table 1 Demographic variables and imaging parameters of patients and controls.

From: Structural retinal changes in cerebral small vessel disease

 

Total

CSVD

controls

Age matched CSVD

P1*

P2*

Gender (m/f)

15/21

12/15

3/6

4/5

0.641

0.730

MRI (1.5 T/3 T)

22/14

17/10

5/4

6/3

0.747

0.730

Fazekas (score 0/1/2/3)

9/14/10/3

0/14/10/3

9/0/0/0

0/5/4/0

  

Fazekas (median; IQR)

1; 2

1; 1

0;0

1; 1

< 0.001

< 0.001

Age (years)

63 ± 10

65 ± 11

57 ± 5

57 ± 4

0.073

1.000

MoCA

25 ± 4

25 ± 4

25 ± 3

26 ± 3

0.971

0.436

Cognitively impaired49

19%

22%

11%

11%

  

WMRI

0.408 ± 0.663

0.536 ± 0.724

0.025 ± 0.027

0.232 ± 0.292

< 0.001

0.006

NOL

14 ± 9

17 ± 9

6 ± 6

13 ± 9

< 0.001

0.031

Total retina volume (mm3)

2.32 ± 0.01

2.31 ± 0.11

2.36 ± 0.07

2.31 ± 0.08

0.101

0.136

  1. Values are mean ± SD and the volume of the retina corresponds to the foveal and parafoveal volumes (3-mm-circle). *Mann–Whitney-U-test was performed to compare the groups. P1, comparison between all patients and controls; P2, comparison between age matched patients and control. Significant results (p < 0.05) are displayed in bold.
  2. CSVD, patients with cerebral small vessel disease; MRI, device used for MRI imaging; 1.5 T, Philips Ingenia 1.5 T; 3 T, Achieva TX 3 T, m, male; f, female; Fazekas, Fazekas score; IQR, interquartile range; MoCA, Montreal Cognitive Assessment; WMRI, white matter lesions volume ratio index; NOL, number of white matter lesions.
Back to article page