Table 2 Comparison of structural retinal parameters between patients with cerebral small vessel disease and age-matched controls.

From: Structural retinal changes in cerebral small vessel disease

Parameter

Controls

CSVD

P*

GCL (mm3)

0.34 ± 0.02

0.30 ± 0.02

0.008

Foveal

0.01 ± 0.00

0.01 ± 0.00

0.730

Pf. nasal

0.08 ± 0.01

0.07 ± 0.00

0.014

Pf. inferior

0.08 ± 0.01

0.07 ± 0.01

0.019

Pf. temporal

0.08 ± 0.00

0.07 ± 0.01

0.063

Pf. superior

0.08 ± 0.00

0.07 ± 0.01

0.011

IPL (mm3)

0.28 ± 0.02

0.27 ± 0.02

0.094

INL (mm3)

0.27 ± 0.02

0.27 ± 0.02

1.00

OPL (mm3)

0.22 ± 0.06

0.20 ± 0.02

0.340

ONL (mm3)

0.51 ± 0.06

0.55 ± 0.03

0.094

RPE (mm3)

0.11 ± 0.02

0.10 ± 0.02

0.387

pRNFL (µm)

75 ± 6

72 ± 4

0.222

MRW (µm)

341 ± 66

333 ± 65

0.796

  1. Values are mean ± SD and the volumes of the macular layers correspond to the foveal and parafoveal volumes (3-mm-circle). *Mann–Whitney-U-test was performed to compare the two groups. Significant results (p < 0.05) are displayed in bold.
  2. CSVD, patients with cerebral small vessel disease; GCL, ganglion cell layer; pf., parafoveal; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium; pRNFL, peripapillary retinal nerve fiber layer; MRW, Bruch’s membrane opening-minimum rim width.
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