Figure 1
From: Plasma taurine is an axonal excitability-translatable biomarker for amyotrophic lateral sclerosis
(a) Principal component analysis (PCA) of plasma metabolites in controls (n = 20) and amyotrophic lateral sclerosis (ALS) patients (first ALS group, n = 7). Two-dimensional plot of PCA scores of PC4 and PC5 in control subjects (black) versus ALS patients (blue) as analyzed according to the normalized values of plasma metabolites detected in participants in the pilot study. (b) Receiver operating characteristic (ROC) curve analysis using the values of the top four statistically significant metabolites (3-methoxytyrosine, dyphylline, N6-acetyllysine, and ribose-5-phosphate) from controls and ALS patients. PC principal component, AUC area under the curve.
