Table 2 Characteristic of the first amyotrophic lateral sclerosis group (n = 7).
From: Plasma taurine is an axonal excitability-translatable biomarker for amyotrophic lateral sclerosis
Number of patients | 7 |
|---|---|
Male/female | 2/5 |
Age, y, mean (SE) | 63.0 (3.1) |
Age at onset, y, mean (SE) | 61.8 (3.1) |
ΔFRS, mean (SE) | 0.39 (0.07) |
Site of symptom onset | |
Bulbar | 3 |
Upper limbs | 3 |
Lower limbs | 1 |
Height, cm, mean (SE) | 162.3 (1,5) |
Body weight, kg, mean (SE) | 56.9 (3.9) |
BMI, mean (SE) | 21.6 (1.5) |
%FVC, %, mean (SE) | 92.2 (3.8) |
CMAP amplitude in median nerve, mV, mean (SE) | 5.5 (1.2) |
Nerve excitability properties | |
SDTC, ms, mean (SE) | 0.46 (0.05) |
TEd (10–30), %, mean (SE) | 75.4 (2.0) |
TEd (90–100), %, mean (SE) | 57.1 (2.4) |
TEh (90–100), %, mean (SE) | − 152.3 (5.8) |
Supernormality, %, mean (SE) | − 33.7 (4.6) |
Complications | |
Hypertension, n (%) | 0 |
Dyslipidemia, n (%) | 0 |
Hyperuricemia, n (%) | 0 |
Other comorbidities | Hashimoto disease 1 (10%) |