Table 3 Statistically significant metabolites in seven amyotrophic lateral sclerosis (ALS) patients vs 20 controls.

From: Plasma taurine is an axonal excitability-translatable biomarker for amyotrophic lateral sclerosis

Metabolites

ALS/control ratio

p-value

Ribose 5-phosphate

2.28

 < 0.0001

N6-acetyllysine

0.35

 < 0.0001

Dyphylline

1.36

 < 0.0001

3-Methoxytyrosine

0.31

0.0001

7-Methylguanine

0.38

0.0003

Butyrylcarnitine

0.43

0.0013

N-Acetylgalactosamine/N-Acetylmannosamine/N-Acetylglucosamine

0.57

0.0016

N-Acetylputrescine

0.34

0.0039

Imidazole lactic acid

0.50

0.0040

Octanoylcarnitine

0.51

0.0061

Urocanic acid

0.47

0.0066

5-Oxoproline

0.83

0.0093

Creatinine

0.72

0.0093

Taurine

1.19

0.0112

Cystine

1.20

0.0263

Pelargonic acid

0.78

0.0478

Glutamine

1.11

0.0478

  1. P-values were obtained by Wilcoxon’s test, comparison of ALS patients and controls.
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