Table 2 Correlations of weighted and non-weighted ISI with visual acuity, central macular thickness, and levels of cytokines.

From: Clinical significance of metabolic quantification for retinal nonperfusion in diabetic retinopathy

 

BCVA

CMT

Ang-1

Ang-2

MCP-1

IL-8

IL-6

PDGF-AA

PlGF

VEGF-A

R

P

R

P

R

P

R

P

R

P

R

P

R

P

R

P

R

P

R

P

Nonperfusion region with leakage

Non-weighted

0.242

0.680

0.284

0.127

− 0.052

0.468

0.068

0.321

0.345

0.065

0.284

0.041*

0.218

0.039*

0.045

0.874

0.380

0.674

0.340

0.173

Weighted ISI

0.319

0.472

0.485

0.040*

0.179

0.352

0.372

0.051

0.456

0.034*

0.448

0.010*

0.336

0.018*

0.312

0.287

0.481

0.012*

0.574

0.010*

Cone

0.428

0.011*

0.447

0.038*

− 0.062

0.667

0.148

0.144

0.431

0.041*

0.369

0.020*

0.304

0.034*

0.287

0.191

0.429

0.040*

0.519

0.038*

Rod

0.226

0.020*

0.421

0.025*

0.146

0.479

0.279

0.056

0.470

0.023*

0.453

0.015*

0.413

0.029*

0.349

0.078

0.478

0.008*

0.542

0.012*

Ganglion cell

0.116

0.132

0.163

0.411

0.532

0.243

0.367

0.068

0.242

0.062

0.217

0.124

0.147

0.104

0.227

0.412

0.347

0.054

0.223

0.060

Nonperfusion region without leakage

Non-weighted

0.121

0.655

0.175

0.346

− 0.062

0.436

− 0.075

0.524

− 0.068

0.512

0.255

0.063

0.195

0.057

− 0.012

0.823

− 0.064

0.453

− 0.120

0.487

Weighted ISI

0.124

0.438

0.136

0.464

− 0.126

0.418

− 0.032

0.893

− 0.052

0.776

0.282

0.038*

0.273

0.020*

− 0.020

0.673

0.057

0.566

0.023

0.840

Cone

0.156

0.345

0.140

0.982

− 0.174

0.325

− 0.115

0.562

0.061

0.715

0.262

0.041*

0.263

0.010*

0.325

0.434

0.113

0.693

0.210

0.462

Rod

0.085

0.636

0.184

0.770

− 0.112

0.513

0.043

0.648

0.043

0.766

0.303

0.030*

0.324

0.026*

− 0.132

0.731

0.179

0.284

0.078

0.645

Ganglion cell

0.047

0.647

0.097

0.612

− 0.131

0.332

0.074

0.577

0.052

0.734

0.145

0.632

− 0.179

0.346

− 0.064

0.695

0.086

0.513

0.034

0.742

  1. P-values were calculated using Spearman correlation.
  2. BCVA best-corrected visual acuity, CMT central macular thickness, ISI ischemic index, R Spearman correlation coefficient.
  3. *P < 0.05.