Figure 2 | Scientific Reports

Figure 2

From: Evaluating diagnostic accuracy and determining optimal diagnostic thresholds of different approaches to [68Ga]-DOTATATE PET/MRI analysis in patients with meningioma

Figure 2

Axial images of [68Ga]-DOTATATE PET AC (A), 3D T1 post-gadolinium MR (B), fused PET/MR T1 (C–E) windowed SUV 0–15. This representative patient from the cohort is a 70-year-old female with a history of WHO grade II meningioma s/p resection and proton therapy 6 years prior to imaging and an additional proton therapy a year prior. The fused PET/MR images demonstrate a lesion suspicious for a meningioma in the left anterior temporal pole with SUV of 13.6 (C, red arrow). The more posteriorly located enhancing lesion (C, white arrow) demonstrates SUV of 4.5 and was suspicious for post-treatment change, given that the SUV of the superior sagittal sinus was 2.3. The subsequent resection and biopsy of the two lesions a year later confirmed the suspected diagnosis of recurrent meningioma and radiation necrosis, respectively. The superior sagittal sinus (D, arrow) demonstrates SUV of 2.3 and the pituitary gland (E) demonstrates SUV of 12.4.

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