Figure 3 | Scientific Reports

Figure 3

From: ICAM-1 related long noncoding RNA is associated with progression of IgA nephropathy and fibrotic changes in proximal tubular cells

Figure 3

ICR was upregulated in human proximal tubular HK-2 cells cultured with TGF-β1. (a) The cell morphology of HK-2 cells treated with or without TGF-β1 (10 ng/ml) for 48 h. (b) QPCR analysis after normalization against β-actin showed an increase in the level of ICR in HK-2 cells treated with TGF-β1(10 ng/ml, 24 h and 48 h) compared to the cells without treatment. (c) Representative confocal fluorescence in situ hybridization images showed that ICR was mainly distributed in cytoplasm of HK-2 cells treated with or without TGF-β1 (10 ng/ml) for 24 h. Data are presented as means ± SD of three independent experiments. *P (vs. TGF-β1 0 h) < 0.05, #P (vs. TGF-β1 24 h) < 0.05.

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