Figure 2 | Scientific Reports

Figure 2

From: Vagus nerve stimulation does not improve recovery of forelimb motor or somatosensory function in a model of neuropathic pain

Figure 2

VNS paired with motor rehabilitation fails to improve recovery of skilled forelimb function. (a) Radial nerve injury results in chronic forelimb weakness, indicated by a sustained reduction in success rate on a skilled forelimb motor task. VNS paired with rehabilitative training (Motor Rehab + VNS, n = 8) fails to improve recovery of motor function compared to equivalent rehabilitative training without VNS (Motor Rehab, n = 8). (b) Additionally, VNS paired with motor training also fails to improve recovery of forelimb withdrawal thresholds. Data presented as mean ± SEM. *** denotes p < 0.001 at the indicated timepoints; n.s. denotes not significant group effect.

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