Figure 2
From: Telomere-to-telomere human DNA replication timing profiles
Replication timing (RT) of previously unresolved regions of the human genome. (a) RT profiles for the five acrocentric p-arms. rDNA arrays (gray) remain as gaps in the profile. Regions shown span from the telomere to 5 Mb upstream of the start of the p-most α-satellite higher-order repeat. (b) RT profiles for the large heterochromatin arrays neighboring the centromeres on the q-arms of chromosomes 1, 9, and 16. Regions shown span from the end of q-most α-satellite higher-order repeat to 5 Mb downstream of the last annotated satellite. The RT profile for the lymphoblastoid cell line GM12878 is shown for each region. rDNA loci and satellite arrays larger than 1 Mb are indicated in colored boxes.
