Table 2 Surgical and pathological outcomes.

From: Significance of pelvic lymph node dissection during radical prostatectomy in high-risk prostate cancer patients receiving neoadjuvant chemohormonal therapy

 

Overall (n = 516)

Limited-PLND group (n = 283)

Non-PLND group (n = 233)

P-value

Surgery type, n (%)

 < 0.001

RARP

379 (73.4)

152 (53.7)

227 (97.4)

 

RRP

137 (26.6)

131 (46.3)

6 (2.6)

 

Median operation time, min (IQR)

156 (131–184)

152 (121–182)

161 (138–189)

0.001

Median blood loss, mL (IQR)

50 (20–243)

100 (25–735)

25 (10–50)

 < 0.001

Prostatectomy Gleason score, n (%)

 < 0.001

No residual tumor

55 (10.7)

29 (10.2)

26 (11.2)

 

6 (3 + 3; ISUP GG1)

3 (0.6)

1 (0.4)

2 (0.9)

 

7 (3 + 4; ISUP GG2)

12 (2.3)

1 (0.4)

11 (4.7)

 

7 (4 + 3; ISUP GG3)

63 (12.2)

11 (3.9)

52 (22.3)

 

8 (4 + 4, 3 + 5, 5 + 3; ISUP GG4)

21 (4.1)

19 (6.7)

2 (0.9)

 

9, 10 (4 + 5, 5 + 4, 5 + 5; ISUP GG5)

362 (70.2)

222 (78.4)

140 (60.1)

 < 0.001

Pathological tumor stage, n (%)

0.584

ypT0

55 (10.7)

29 (10.2)

26 (11.2)

 

ypT2

314 (60.9)

168 (59.4)

146 (62.7)

 

ypT3

147 (28.5)

86 (30.4)

61 (26.2)

0.327

Surgical margin positive, n (%)

44 (8.5)

17 (6.0)

27 (11.6)

0.027

Median number of dissected nodes, n (IQR)

 

4 (3–7)

  

Number of positive nodes, n (%)

0

 

281 (99.2)

  

1

 

1 (0.4)

  

2

 

1 (0.4)

  

Biochemical recurrence, n

85

55

30

 

Cancer-specific mortality, n

5

4

1

 

All-cause mortality, n

13

10

3

 

Median follow-up periods, months (IQR)

57 (31–81)

77 (63–94)

34 (20–46)

 < 0.001

  1. PLND pelvic lymph node dissection, RARP robot-assisted radical prostatectomy, RRP retropubic radical prostatectomy, IQR interquartile range, ISUP GG the International Society of Urological Pathology grade group.