Table 1 Important parasites and their associated infectious disease.

From: Compilation of parasitic immunogenic proteins from 30 years of published research using machine learning and natural language processing

Parasite (Genus)^a	Class^b	Phylum	Disease^c	Priority^d
Babesia	Protozoa	Apicomplexa	Babesiosis
Cryptosporidium	Protozoa	Apicomplexa	Cryptosporidiosis	F,W
Cyclospora	Protozoa	Apicomplexa	Cyclosporiasis	F
Eimeria	Protozoa	Apicomplexa	Coccidiosis
Neospora	Protozoa	Apicomplexa	Neosporosis
Plasmodium	Protozoa	Apicomplexa	Malaria
Sarcocystis	Protozoa	Apicomplexa	Sarcocystosis	F
Theileria	Protozoa	Apicomplexa	Theileriosis
Toxoplasma	Protozoa	Apicomplexa	Toxoplasmosis	F,W
Trypanosoma	Protozoa	Euglenozoa	Trypanosomiasis, dourine, surra	F,G,W
Balantidium	Protozoa	Ciliophora	Balantidiasis	F
Ichthyophthirius	Protozoa	Ciliophora	White spot
Entamoeba	Protozoa	Evosea	Amebiasis	F,W
Leishmania	Protozoa	Euglenozoa	Leishmaniasis	G,W
Dientamoeba	Protozoa	Metamonada	Dientamoebaisis
Giardia	Protozoa	Metamonada	Giardiasis	F,W
Histomonas	Protozoa	Metamonada	Histomoniasis
Trichomonas	Protozoa	Metamonada	Trichomoniasis
Ancylostoma	Helminthic	Nematoda	Ancylostomiasis, hookworm	G,W
Angiostrongylus	Helminthic	Nematoda	Angiostrongyliasis
Ascaris	Helminthic	Nematoda	Ascariasis	F,G,W
Baylisascaris	Helminthic	Nematoda	Baylisascariasis
Cooperia	Helminthic	Nematoda	Infection only
Dirofilaria	Helminthic	Nematoda	Dirofilariasis/heartworm
Dracunculus	Helminthic	Nematoda	dracunculiasis, guinea worm	G,W
Enterobius	Helminthic	Nematoda	Enterobiasis
Gnathostoma	Helminthic	Nematoda	Gnathostomiasis
Haemonchus	Helminthic	Nematoda	Haemonchosis
Loa	Helminthic	Nematoda	Loiasis
Necator	Helminthic	Nematoda	Necatoriasis, hookworm	G,W
Onchocerca	Helminthic	Nematoda	Onchocerciasis	G,W
Pseudoterranova	Helminthic	Nematoda	Anisakiasis	F
Strongyloides	Helminthic	Nematoda	Strongyloidiasis
Teladorsagia	Helminthic	Nematoda	Teladorsagiosis
Toxocara	Helminthic	Nematoda	Toxocariasis
Trichinella	Helminthic	Nematoda	Trichinellosis	F,W
Trichostrongylus	Helminthic	Nematoda	Trichostrongylosis
Trichuris	Helminthic	Nematoda	Trichuriasis	F,G,W
Wuchereria	Helminthic	Nematoda	Filariasis	G,W
Clonorchis	Helminthic	Platyhelminthes	Clonorchiasis	W
Diphyllobothrium	Helminthic	Platyhelminthes	Diphyllobothriasis	F
Dipylidium	Helminthic	Platyhelminthes	Infection only
Echinococcus	Helminthic	Platyhelminthes	Echinococcosis	F,W
Fasciola	Helminthic	Platyhelminthes	Fascioliasis	F,W
Fasciolopsis	Helminthic	Platyhelminthes	Fasciolopsiasis
Hymenolepis	Helminthic	Platyhelminthes	Hymenolepiasis
Moniezia	Helminthic	Platyhelminthes	Infection only
Opisthorchis	Helminthic	Platyhelminthes	Opisthorchiasis	F,W
Paragonimus	Helminthic	Platyhelminthes	Paragonimiasis	F,W
Schistosoma	Helminthic	Platyhelminthes	Schistosomiasis	G,W
Taenia	Helminthic	Platyhelminthes	Cysticercosis	F,W
Haemaphysalis	Ectoparasite	Arthropoda	Disease vector
Ixodes	Ectoparasite	Arthropoda	Paralysis
Lucilia	Ectoparasite	Arthropoda	Flystrike

^aParasite = the genus of an organism that lives on or in a host organism and typically at the detriment of the host (genus is a taxonomic name defining a group of related living organisms made up of one or more species).
^bClass = there are three main classes of parasites that can cause disease in humans and livestock: (1) protozoa (microscopic single-celled eukaryotes); (2) helminthic (multicellular organisms generally visible to the naked eye in their adult stages); and (3) ectoparasite (ticks, fleas, lice, and mites that attach or burrow into the skin).
^cDisease = the name given to an abnormal condition detrimentally affecting the structure or function of all or part of a host organism due to parasite infection. ‘Infection only’ signifies multiplication of parasites occurs within or on a host’s body but does not disrupt the normal functioning of the host.
^dPriority = F,G,W denotes priority diseases in need of a vaccine as determined by: (F) Food and Agriculture Organization of the United Nations (FAO)—Microbiological Risk Assessment series (https://www.who.int/publications/i/item/microbiological-risk-assessment-series); (G) Bill and Melinda Gates Foundation—Neglected Tropical Diseases (https://www.gatesfoundation.org/our-work/programs/global-health/neglected-tropical-diseases) and Uniting to Combat Neglected Tropical Diseases (https://unitingtocombatntds.org/ntds/); and (W) World Health Organisation (WHO) – Ending the neglect to attain the Sustainable Development Goals: A road map for neglected tropical diseases 2021–2030 (https://www.who.int/publications/i/item/9789240010352). URLs last viewed September 2021.

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Table 1 Important parasites and their associated infectious disease.

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