Table 3 Manual verification of vaccine candidates derived from automated extraction of names from published abstracts.

Candidate	UniProt ID	H	PubMed ID	Year	Species	Prot
Circumsporozoite protein	A0A4V0KF74 Q03752 A0A077Y0S6	80	22252877	2011	Plasmodium. yoelii	Yes
Citrate synthase	False positive	27	8817831	1996	Plasmodium berghei	No
Microneme protein MIC3	B2D1U3	20	21632181	2011	Toxoplasma gondii	Yes
Liver stage antigen	Q25893	15	8609407	1996	Plasmodium falciparum	Yes
Rhoptry associated protein-1	A7AS21	12	12933845	2003	Babesia bovis	No^a
Putative kunitz-type protease inhibitor	A0A3Q0KUE0 A0A3Q0KFV5 A0A5K4F6V0 G4VEE0 A0A3Q0KN03 G4VBB1 G4VED8	1	31736947	2019	Schistosoma mansoni	Yes
Ribonuclease T2	Q6PYW1	1	28212670	2017	Schistosoma japonicum	Yes
Thioredoxin-like	A0A1N6LW58	1	29335000	2018	Babesia microti (strain RI)	No
Hydatid disease diagnostic antigen P-29	Q9U8G7	0	32908913		Echinococcus granulosus	Yes
Surface antigen 22	Q70CC3	0	33689009	2021	Eimeria tenella	Yes

Candidate = a protein name taken from sheet [Unique Names] in Supplementary Table S4. This sheet lists 438 unique names from the 1099 representative names extracted from the 1776 positively classified abstracts. The 324 unique names without a warning are considered possible vaccine candidates. Candidates with the highest and lowest h-indexes were chosen from the list at regular row intervals for manual verification; UniProt ID. = UniProt ID(s) linked to candidate name (names are mapped via sheets [Representative Names] and [Clusters] in Supplementary Table S4). Multiple IDs per candidate are representatives from different clusters. UniProt IDs underlined exactly match to the protein identifier in the publication; H. = h-index of the protein names’ source publications; Year = year of publication; Species = the source species for the protein; Prot. = ‘Yes’ or ‘No’ whether the publication reports testing for protein immunogenicity in an animal model.
^aProtein reported in other publications as a possible vaccine candidate.

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