Figure 3

Relation between fatality risk and glucose variability. Continuous hazard ratios for fatality or non-survival were calculated by Cox proportional hazard models of daily glycaemic variability (DGV) adjusted for age and sex, including 95% CI for endpoint. The dashed red line notates a hazard ratio of 1.0, the solid black line the dichotomisation threshold, which we determined using a regression tree. The threshold of 25.5 mg/dl for DGV was used for our summary statistics (Tables 1 and 2), Kaplan–Meier curves (Fig. 4) and the adjusted DGV Cox proportional hazard model (Fig. 5).